Discussion
Before any acquisition of pooling echocardiographic data for research
and clinical applications, a process of quality control and reading
harmonization measurements should be undertaken.13-16The present results demonstrate that a rigoroursly designed protocol
with a strong focus on quality assurance and certification can yield
very strong ICC and limited variability among the 19 participant
experienced centers to a large prospective EDE study of the right heart
and the pulmonary circulation.