Strengths of the Study
Our study is one of the largest studies examining the effect ESS on pulmonary outcomes in the CF population and the only study to examine outcomes 2 year post-operatively. This study was limited by its retrospective nature and small cohort size, which is inherent in the CF population. Symptom and endoscopic scores were not examined. The findings of this study can guide further management and research examining sinonasal disease and sinus surgery in the CF population.
Similar to current literature, our results did not show a significant benefit of endoscopic sinus surgery on clinical outcomes including FEV1 and pulmonary exacerbations. Further studies are required to determine improvement in quality of life in patients undergoing endoscopic sinus surgery. Studies examining the effect of aggressive follow-up and management of sinonasal disease in this population are warranted.
CONFLICT OF INTEREST
This study received no funding. There is no potential or actual conflict of interest with respect to this study.
DATA SHARING
The data that support the findings of this study are available from the corresponding author upon reasonable request.
FUNDING STATEMENT
This study received no funding.
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