Strengths of the Study
Our study is one of the largest studies examining the effect ESS on
pulmonary outcomes in the CF population and the only study to examine
outcomes 2 year post-operatively. This study was limited by its
retrospective nature and small cohort size, which is inherent in the CF
population. Symptom and endoscopic scores were not examined. The
findings of this study can guide further management and research
examining sinonasal disease and sinus surgery in the CF population.
Similar to current literature, our results did not show a significant
benefit of endoscopic sinus surgery on clinical outcomes including FEV1
and pulmonary exacerbations. Further studies are required to determine
improvement in quality of life in patients undergoing endoscopic sinus
surgery. Studies examining the effect of aggressive follow-up and
management of sinonasal disease in this population are warranted.
CONFLICT OF INTEREST
This study received no funding. There is no potential or actual conflict
of interest with respect to this study.
DATA SHARING
The data that support the findings of this study are available from the
corresponding author upon reasonable request.
FUNDING STATEMENT
This study received no funding.
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