Statistical Analysis
Biochemical experiments were repeated three times at least. Values are reported as the Means±SEM (GraphPad Prism, San Diego, CA). Statistical comparisions between two groups were analyzed using unpaired two-tailed t test. Statistical comparisions among multiple groups were conducted using one-way ANOVA Test (GraphPad Prism, San Diego, CA). Statistical comparisons for series of data collected at different time points were conducted by ANOVA tests. All statistical tests were unpaired and two-tailed.