WNT Signaling Gene Lists
To analyze all genes within the WNT signaling pathways, the AmiGO2
web-based tool provided by the Gene Ontology (GO) Consortium was used to
retrieve 523 unique Homo sapiens genes under WNT signaling GO
accession number GO:0198738 as listed
in the S1 Text. To evaluate which components of the overarching WNT
signaling pathway were affected, we used other GO-specific gene lists
including WNT protein secretion
(GO:0061355), WNT-related planar cell
polarity (GO:0060071), canonical
WNT/β-catenin signaling (GO:0060070),
and WNT-related calcium modulation
(GO:0007223). These gene lists can
also be found in the S1 Text (Ashburner et al., 2000; Consortium, 2019).