3.1 Study design
This study will follow the international model of Systematic Review and
Meta-analysis, following the rules of PRISMA (preferred reporting items
for systematic reviews and meta-analysis).
Table 1 shows the main variables of the present study that will be
addressed according to the classification of the acronym PICO (P =
Patients; I = Intervention; C = Control; O = Outcomes).
Table 1. PICO chart (Patients; Intervention; Control;
Outcomes).