Efficacy of AF ablation in patients with no or limited LVAs
In this study, group A patients without LVA had a good prognosis up to
the late phase after multiple sessions. This result is consistent with
previous studies of LVA-guided therapy 12-14.
Considering the implications of LVAs on AF development, LVAs reflect
atrial fibrosis15,16 and fibrotic remodeling tissue
leads to slow conduction and short action potential duration, which
facilitates reentry 17,18. In group A patients who did
not have these arrhythmic substrates, many non-PV procedures such as SVC
isolation were performed at the time of additional procedures,
suggesting that if the AF initiator could be treated, the results might
be comparable to those of paroxysmal patients.