Conclusion
RDD is a rare disease and has a relatively benign clinical course, it
often mimics other diseases and malignancies and can easily be
misdiagnosed. In the developing countries like Tanzania, it can easily
be misdiagnosed as Tb adenitis or malignancies like Non- Hodgkin’s
lymphoma. A high index of suspicion is necessary for its diagnosis.
Definitive diagnosis is made by histology which show emperipolesis,
sinus dilatation and histiocytic cells infiltration and
immunohistochemistry reveals positive S100 and CD68 markers, and
negative CD1a marker. Because the disease generally resolves
spontaneously, observation is currently the advocated approach.