(A) Comparison of SPW mean amplitudes at baseline and after meal intake
(90 mins before prucalopride), and in response to intraluminal
prucalopride. *compared to baseline
(* P< 0.05).
(B) An HAPW with mean amplitude of 91 mmHg evoked by intraluminal
prucalopride propagating with a velocity of 0.2 cm
s-1, was associated with 92.8% anal sphincter
relaxation (decrease of anal sphincter pressure from mean amplitude of
51.45 mmHg to 3.70 mmHg) as well as strong urge to defecate which likely
prompted the subject to contract her external anal sphincter to avoid
outflow (black arrow). The white line shows the position of the balloon,
the white arrow shows the relaxed anal sphincter.
(C) 3-D representation of (B).