Patients
Consecutive patients who underwent tumor resection for OOSCC at our
University Hospital from January 2008 to December 2016 were
retrospectively selected. Among them, patients who had a cervical
contrast-enhanced CT scan available within 3 months before surgery were
included. Patients treated with first chemo and/or radiotherapy, with a
history of HNSCC, with too small or not delineable lesion, or with
exaggerated dental artifacts on the CT examination were excluded.
Patients were informed of the study objectives and could express their
opposition to the use of their medical data. The database was
constituted in accordance with the reference methodology MR004 of the
Commission Nationale de l’Informatique et des Libertés (n°2206749,
13/09/2018) and followed the French authorities’ requirements.
The following data were collected: age, gender, body mass index (BMI),
alcohol and tobacco use, precise location of the tumor, HPV status, TNM
staging, histological differentiation, resection status.
Every patient underwent close clinical-biological and radiological
evaluation during the first 3 years after surgery. Primary and secondary
endpoints were OS and EFS, respectively. OS was defined as the time from
diagnosis until death from any cause. Patients alive at the end of
follow up were censored at that time. EFS was defined as the time from
diagnosis until recurrence; metastasis or death from any cause. Patients
without recurrence, death or metastasis at the end of follow-up were
censored at that time.