PCR and LAMP tests exist that meet the TPP threshold for sensitivity and specificity
xx% of tests found in the literature meet the TPP threshold for sensitivity and specificity of xx% and xx% in the TPP. However, xx% of these are based on blood culture. Of those based on patient samples, only xx% meet the necessary criteria.
Some outliers with explanations e.g. LAMP assay with 10% sensitivity was with a particular primer set.
Needed changes:
- Add TPP values threshold line
- Change PCR marker so it is less likely to obscure the other markers
- Breakdown by direct from patient sample and blood culture