Nucleic acid tests (NATs) have higher sensitivity and specificity but are not typically in use in Cameroon or other typhoid-endemic countries due to the complexity of the test design, cost and requirement for laboratory facilities compared to serological tests. There has been numerous scientific publication demonstrating S. Typhi and S. Paratyphi detection by PCR , real-time PCR and loop mediated isothermal amplification (LAMP) (Table 2) \cite{Kaur_2018,Fan2015,Nga2010,Tennant2015,Frickmann_2019,Francois2011})(complete ref) but none are currently in wide use and we were unable to find any laboratories in Cameroon offering molecular diagnosis of enteric fever.