The most commonly used typhoid POC tests (Widal, Typhidot, Tubex, Test-It Typhoid, TPTest) require between 5µL and 1mL of blood, but have only moderate sensitivity and specificity. 23 Survey respondents agreed that an optimal next-generation typhoid RDT would use a capillary blood sample with a volume of ≤100µL, or a less invasive sample type, excluding urine and stool.12 28 However, survey respondents indicated that ≤1mL of venous blood was an acceptable minimum requirement due to the current difficulty in accurately diagnosing typhoid fever (table 3). The TPP allows for up to two sample processing steps as an RDT may require serum to be separated from whole blood, with at most five steps for the test of which no more than two should be timed,28 and a total hands on time of