Uveal Melanoma Causes and Treatments
Unfortunately, the causes for uveal melanoma are currently unclear. However, some studies have revealed that the DNA present within the cancerous cells showed alterations on chromosomes 1,3,6, and 8. They have also found that genes BAP1, SF3B1, GNAQ, and GNA11 seem to play a role in the development of uveal melanoma [5,6]. Although these studies did uncover some genetic errors that may be responsible, they had only analyzed chromosomal rearrangements, and not specific coding mutations. Currently there are no effective therapies for the treatment of UM patients.