CASE PRESENTATION
An 85-year old female with type II diabetes and heart failure, treated with metformin, antihypertensives and antiplatelet drugs, presented to our department with a 4-months history of a rapidly growing mass located within the soft tissues of the right cheek. The lesion was painless and no other signs or symptoms were further reported.
Clinical history did not highlight any local recent event. Patient examination revealed a palpable, round, painless and firm lesion located on the right cheek, without alteration of the overlying skin.
An US scan confirmed the presence of the a 25mm nodular mass adherent to the fascia without local neck nodes involvement.
Soon after, the patient underwent complete surgical excision of the lesion under local anesthesia which was easily obtained by a small intraoral access. Definitive histopathological examination of the surgical specimen showed atypical fibrocytes and histiocytes proliferation in a fibromixoid stroma. The cells resulted negative for the presence of S-100, cytokeratin AE1-AE3 and desmin, and thus diagnosis of Nodular Fasciitis (NF) was made.
At Two-years follow-up there was no local recurrence.