Microarray data analysis
For the microarray datasets (GSE17400, GSE19580), the data was analysed
using the online Geo2R tool (default options) to determine the
differential expression of genes between control and the target set and
the output file containing a list of differentially expressed genes was
downloaded. Amongst these genes, only those whose regulation was
significant (adj. p<=0.05) were uploaded in the NetworkAnalyst
software and downstream analysis was done in an identical manner to that
in the RNA-seq data analysis.