Fecal microbiota diversity
To assess the effects of PSL treatment on intestinal microbiota in type
1 AIP, we performed next generation sequencing of 16S rRNA in fecal
samples, as previously described [20, 22]. Fecal microbial diversity
was comparable before and after PSL treatment, as judged by the
rarefaction analysis of alpha diversity (Fig. 1D) and by the Shannon
index (data not shown).