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Bronchiectasis Associated with Electronic Cigarette Use: A Case Series
  • +1
  • Eric Mull,
  • Brent Adler,
  • Richard Shell,
  • Melissa Holtzlander
Eric Mull
Nationwide Children's Hospital
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Brent Adler
Nationwide Children's Hospital
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Richard Shell
Nationwide Children’s Hospital
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Melissa Holtzlander
Nationwide Children's Hospital
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Peer review status:UNDER REVIEW

25 May 2020Submitted to Pediatric Pulmonology
26 May 2020Submission Checks Completed
26 May 2020Assigned to Editor
27 May 2020Reviewer(s) Assigned
10 Jun 2020Review(s) Completed, Editorial Evaluation Pending
10 Jun 2020Editorial Decision: Revise Major
28 Jun 20201st Revision Received
29 Jun 2020Assigned to Editor
29 Jun 2020Submission Checks Completed
29 Jun 2020Reviewer(s) Assigned
13 Jul 2020Review(s) Completed, Editorial Evaluation Pending
14 Jul 2020Editorial Decision: Revise Minor
03 Aug 20202nd Revision Received
04 Aug 2020Assigned to Editor
04 Aug 2020Submission Checks Completed
04 Aug 2020Reviewer(s) Assigned

Abstract

Bronchiectasis (BE) is defined as a permanent, irreversible dilation of the bronchial tree. In the pediatric population, this disease process is most commonly associated with patients with Cystic Fibrosis (CF). However, bronchiectasis unrelated to cystic fibrosis is increasingly noted as a cause of chronic respiratory related morbidity worldwide. Chronic inflammation and recurrent infection result in cellular cascades that lead to irreversible structural changes of the airways. When these architectural changes occur, they confer extensive risks to morbidity usually due to continued infections. In the adult population, bronchiectasis has been associated with chronic obstructive pulmonary disease, which is mainly caused by cigarette smoking. In this report, the authors reviewed various cases of bronchiectasis in the pediatric population where the only inciting factor was electronic cigarette use.