Materials and Method
The Ethics Committee’s approval of this study was taken from[removed for blind peer review] Ethics Committee with the file number of 2018/716.
In this study, all patients who underwent open or transoral laser surgery for laryngeal malignancies or biopsied for the suspicion of a laryngeal malignancy in a tertiary university hospital’s Ear Nose Throat and Head and Neck Surgery clinic between the years 2006 – 2017 were evaluated.
All patients with pathology result other than vSCC (conventional SCC and non-SCC laryngeal malignancies) were excluded from the study. A retrospective chart analysis was made for all patients with a definite vSCC pathology report including information of sex, age at the time of diagnosis, localization of the primary lesion, TNM stage at the time of diagnosis, primary treatment modality (surgery, radiotherapy (RT) or chemoradiotherapy (CRT), adjuvant treatment modalities if available and cause of death for the patients who died during the follow-up. Overall survival, disease-free survival and overall follow-up period was calculated as months.
Lastly, preoperative and postoperative pathology reports of surgically treated patients were compared to analyze whether a difference exists between preoperative results from small biopsy specimens and definite pathology reports form the excision material.
Microsoft Excel Volume 15.31 (170216) and SPSS 21.0 programs were used for the statistical analysis of the study. Kaplan – Meier analysis was used for the survival analysis.