Table 1. Changes of spontaneous synaptic events recorded in CR, CCK-SCA and pyramidal cells after bath-application of a5-SOP002 in 10-12 months of age-matched, wild-type and APPNL-F/NL-F mice.  sIPSP, spontaneous inhibitory postsynaptic potential. sEPSP, spontaneous excitatory postsynaptic potentials;  * P  < 0.05,  **P  <0.01 . Values represent average values in control and after bath-application of a5-SOP002 ± SEM. A one-way ANOVA followed by post-hoc Tukey’s test for multiple comparisons was used to determine the statistical value. A paired, two-tailed Student’s t-test was utilised for direct comparison between two cohorts when Tukey’s test was not utilised. Sample size n denotes the number of animals (one cell per animal was recorded in these experiments).