3|RESULTS
Finally, the LVAS group was composed of 70 children (boys, 58.57%) with
a median age of 28.50 months (range 6-72 months) (TABLE 1). As TABLE 1
shown that the hearing thresholds of ASSR and behavior audiometry were
both belong to the profound hearing loss. The difference between
binaural hearing was 13.57±13.27 dB nHL with 54.29% of symmetric
binaural hearing rate. 70 gender-, age-, and auditory- matched children
were recruited as non-LVAS group. As TABLE 1 shown that, there was no
significant difference in gender(P= .396), age(P= .959), and
auditory level (all P> .05) between the two groups.
Compared with the normal developmental criteria of 85 score in Gesell
schedule, LVAS children and non-LVAS children both had developmental
delay (TABLE 1, FIGURE 2). For LVAS children, the delay occurred in
full-dimensional developments including gross motor, fine motor,
adaptability, language, and social skill (all P< .05)
(FIGURE2). Whereas, for non-LVAS group, the delay didn’t occurre in
gross motor(P= .199) (FIGURE 2).
Dividing the development results into four gradings (as shown in TABLE
2), for the above two groups, in terms of overall developments, majority
of children were both distributed in mild neurological damage, similar
distributions were found in the sub-developments of fine motor,
language, adaptability, and social skill. Whereas, in gross motor,
majority of children had the near-normal developments. The specific and
detailed distribution rates were shown in TABLE 2. According to the
above results, the language development was the worst, followed by
social skills, adaptability, and fine motor, whereas gross motor was the
best (TABLE 1-2, FIGURE 2).
Then, the developments were compared between the LVAS and non-LVAS
groups. There was no difference in developments score including all
sub-dimensional developments (all P> .05) (TABLE1,
FIGURE 3) and similar results were found in the grading of developmental
level (all P> .05) (TABLE 2). Although the difference
results in gross motor in comparison with normal criteria, there was no
significant difference between the two groups(P= .673) (TABLE1,
FIGURE 3).
Subsequently, the multivariate linear regression was performed to assess
the relative contributions of corresponding variables to developments of
LVAS children. The results showed that only age was the related factors
to overall development (B =-.253, P< .05)
including sub-developments of gross motor, adaptability and social skill
(all B <0, all P< .05) (TABLE 3). In
order to explore the effect of age on the developments, LVAS subjects
were divided into three groups: 6-12 months, 12-36 months and 36-72
months. Developmental scores of these three groups were provided in
TABLE 4. Compared among the three age groups, significant differences
were found in overall development (P= .001) including
sub-developments of adaptability, language and social skill (allP< .05) but not in gross and fine motor (allP> .05). We further made multiple comparisons in any
two age groups. In gross and fine motor, there appeared significant
difference in 6-12 months’ and 12-36 months’ group (allP< .05). In addition, compared with 6-12 months’ group,
the overall development in 12-36 months and 12-36 months’ group had
lower developmental scores (P= .022, P= .003, respectively),
whereas, there was no significant difference between 12-36 months and
12-36 months’ group (P= .205). Similar results appeared in fine
motor and adaptability (all P< .05) (TABLE 4).