Results
The demographic characteristics of the 39 patients taking part in the
study were similar between the two groups and are summarized in Table 1.
Examination of the study groups in terms of ADA values revealed a
significant difference between the two groups 20 min after removal of
the cross-clamp (p=0.020), while other measurements were higher in the
DNS group, although the differences were not significant
(p>0.05 for all). Comparison of the two groups in terms of
time-dependent changes in ADA values revealed that the difference was
significant[F (3, 102) =2.64 p=0.043 ƞ2=0.082].
XOD values in the DNS were higher than those in the IWBC group at all
time points, and significant differences were observed 20 min after
removal of the cross-clamp and before cross-clamp removal(p=0.023 and
p=0.001, respectively). When values were examined in terms of time, the
differences were significant[F (3, 108) =10.26 p=0.017 ƞ2=0.217].
CK-MB, SOD, native thiol, total thiol, and thiol disulfide measurement
values did not differ between the groups at any time point.No difference
was also observed in troponin in the first three measurements, although
a significant difference was found between the two groups 20 min after
cross-clamp removal (4th measurement p=0.032).
Analysis of the groups in terms ofPON andarylesterase parametersshowed
that both decreased significantly at measurements performed 20 min after
cross-clamp removal and before cross-clamp removal, producing a
time-dependent difference (PON [F (3, 108) =3.92 p=0.011 ƞ2=0.098];
arylesterase [F (3, 108) =3.39 p=0.021 ƞ2=0,086]). However,
intergroup comparisons showed that the differences between the groups at
the same time points were not significant(Table 3).