2.5 Outcomes
The primary outcome of interest was the composite of the any of the
following medical resource uses during the follow-up-period:
hospitalization of all-causes, laboratory/radiological services, and
systemic antibiotics use. These outcome events were identified by claims
records for procedures and medications. For laboratory services, any of
the complete blood count, chemical panel or rapid antigen tests were
assessed. Radiological examination represented plain radiography
regardless of sites. As secondary outcomes, each component of the
primary outcomes and return visit to medical institutions within 9 days
were compared between the baloxavir and NAIs groups. These outcomes were
prespecified prior to data analysis.