Conclusion:
Our study results supported the data that performing CNS prophylaxis
with triple intrathecal therapy in pediatric patients with ALL and early
recognition of patients with a high probability of relapse with MRD
follow-ups increase patient survival rates. However, improving treatment
protocols and early detection of patients with a high probability of
relapse alone are not sufficient to increase survival rates, especially
in developing countries. In order to prevent deaths due to infections in
LICs, it is necessary to take social and economic measures as well as
medical studies.
Special thanks: The authors thank the esteemed Dr. C-H Pui for sharing
your valuable opinions with us.