Bullfrog is one of the most important economic aquatic animals in China.
It is widely cultured in southern China, and is a key breed recommended
by China's poverty alleviation industry. In recent years, a fatal
bacterial disease often occurs in cultured bullfrogs. The clinical
manifestations of diseased bullfrog were severe intestinal inflammation
and even anal prolapse. A bacterial pathogen was isolated from the
diseased bullfrog intestine. The bacterium was identified as Vibrio
cholerae by morphological, biochemical and 16S rRNA phylogenetic
analysis. In this study, V. cholerae was isolated and identified from
the diseased bullfrog for the first time, which provided the basis for
the diagnosis and control of the disease. At the same time, it is also
reminded that V. cholerae from bullfrog may be transmitted to human
through bullfrog food and aquaculture water, which is a serious threat
to human beings. The whole society should pay attention to it and
formulate reasonable measures to avoid disasters.