Lung biopsy
Histopathologic findings of lung biopsy revealed diffuse alveolar damage
(DAD) in early phase which was characterized by interstitial edema with
focally fibrinous exudates and hyaline membranes. Intra-alveolar
hemorrhage with mild interstitial inflammation consisted of lymphocytes
and histiocytes and focal parenchymal necrosis were identified. Focal
alveolar destruction was seen. Also large multinuclated pneumocytes
without evidence of intranuclear or cytoplasmic inclusion was noted.
There was no evidence of mucus plugging with in airways. No granuloma or
eosinophilic infiltration were identified.