Data collection
A clinical history revision of the included patients was performed,
focusing mainly at patients’ consulting disease, comorbidities and the
treatments being currently followed by them (Supplementary Table
1 and Supplementary Table 2 ). Briefly, diabetes, pulmonary
disease, cardiovascular (CV) disease and chronic kidney disease were
registered if they were present in the clinical history. In the case of
arterial hypertension (AHT) and transplantation, they were only recorded
if patients were receiving treatment with specific drugs for those
comorbidities. Finally, cancer was recorded only if the patient had an
active process or was following a treatment for a previous cancer,
during the studied period.
The primary outcome was the presence of confirmed or
highly suspected symptomatology of
COVID-19 (hsCOVID-19) informed both at the hospital or at the primary
care centre, from the 1st to the
29th of March 2020. Following the Spanish health
authorities’ recommendation for the identification in primary care
centres of patients with unconfirmed symptoms of SARS-CoV-2 infection,
it was considered that patients presented symptoms when they reported
fever (defined as axillary temperature >37ºC) and shortness
of breath and/or cough. If only fever was present, it was only
considered as symptoms if it came with at least two of the following
symptoms: anosmia, ageusia, rhinorrhea, diarrhea of one week of
evolution, pharyngitis, odynophagia or arthromyalgia.