Conclusion
An increased prevalence of overweight and obesity was observed in our pediatric post-transplant population, with older children at highest risk. In addition, patients without total body irradiation as part of the conditioning regimen experienced more weight gain than patients who received total body irradiation. Due to the well-documented negative effects of excess adiposity on health, it is crucial to optimize body composition during the pre-treatment, treatment, and post- treatment periods to mitigate the risk of catastrophic adverse events later in life. Additional studies characterizing the interaction between body composition and hematopoietic cell transplant outcomes are warranted. Greater insight into this field will undoubtedly provide guidance on the identification of at-risk populations and the development of interventions to treat and prevent obesity.