Figure 3. Functional clustering of GNL3-regulated genes. (A) The top ten representative GO biological processes of GNL3 down-regulated genes. (B) The top ten representative KEGG pathways of GNL3 down-regulated genes. (C) IGV-sashimi plot shows a repression of IL24 expression after GNL3 knockdown. The exon sequences are denoted by boxes and intron sequences by the horizontal line. (D) IGV-sashimi plot shows a repression of PTN expression after GNL3 knockdown. (E) q-RT-PCR of IL24 gene in HeLa cells. (F) q-RT-PCR of PTN gene in HeLa cells.