2.1 Virus and Cells
SARS-CoV-2 strain BetaCoV/Germany/BavPat1/2020 (kindly provided by Charité Universitätsmedizin, Institute of Virology, Berlin, Germany; EVAg 026V-03883) was used for all inoculations.
CHO cells (Chinese hamster ovary, ATCC CCL-61), Vero cells (African green monkey kidney epithelial, CCL-81, sourced from the ECACC 84113001), HEK-293 cells (Human embryonic kidney cell line, ATCC CRL-1573), HT-1080 cells (Human fibrosarcoma cell line, ATCC CCL-121), and MRC-5 cells (human lung fibroblast, ATCC CCL-171) were used.