Sources of
Funding
This work is supported by the Kaifeng Excellent Key Laboratory Grant
(Grant no. 20190601A) British Heart Foundation (BHF) (PG/14/79/31102,
and PG/15/12/31280 and BHF Centres for Research Excellence (CRE) at
Cambridge, CLHH, PG/14/80/31106, PG/16/67/32340, ML, PG.
FS/17/52/33113,AT) and Oxford (ML) the Chinese Natural Science
Foundation (31171085: ML) and EPSRC (United Kingdom) (EP/J00958X/1 and
EP/I029826/1) (HZ).
Disclosures
The authors have declared that no conflict of interest exists.
Author contributions
GH, CL, AT, DP, CLHH, HZ and ML contributed to the study design
GW, XT, GH, YN, LW, XJ, GH contributed to the electrophysiological data
acquisition.
GW, YD, GH, YX, LW, DL and NH contributed to the data analysis and
visualization.
HF, KZ, HZ contributed to the action potential computer simulation.
PM and ML contributed to the molecular docking computer simulation.
LW, DP, ML and GH contributed to the funding and resource acquisition.
ML and GH contributed to the supervision.
All authors contributed to the writing.