loading page

A Saudi family with sickle cell disease presented with acute crises and COVID-19 infection, a case report
  • Thumbnail
  • +4
  • ABDULQADER AL-HEBSHI,
  • Mohammed Zolaly,
  • Amer Alshengeti,
  • Ghaya Al Qurainees,
  • Sofyan Yamani,
  • Naif Hamdan,
  • Turki Alwasaidi
ABDULQADER AL-HEBSHI
National Guard Health Affairs
Author Profile
Medium
Mohammed Zolaly
Taibah University College of Medicine
Author Profile
Amer Alshengeti
Taibah University College of Medicine
Author Profile
Ghaya Al Qurainees
National Guard Health Affairs
Author Profile
Sofyan Yamani
National Guard Health Affairs
Author Profile
Naif Hamdan
National Guard Health Affairs
Author Profile
Medium
Turki Alwasaidi
Taibah University College of Medicine
Author Profile

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a new infectious agent causing the ongoing coronavirus disease 2019 (COVID-19) pandemic since December 2019. The most severe disease and mortality due to COVID-19 occur in patients with comorbidities. Sickle cell disease (SCD) patients are considered immunocompromised due to the loss of splenic function. Here we report three cases of COVID-19 in one family affected by SCD. A mother and two siblings were diagnosed with COVID-19. The two siblings, 14 and 12 years, presented with vaso-occlusive crisis and one subsequently developed acute chest syndrome (ACS). All family members had favorable outcomes.