Limitations
This study has several limitations. This study is retrospective in design and not randomized. As such, its results may be prone to selection bias which may have influenced the results. The causes of prolonged CPB times were not captured in this data registry but may influence the results. Similarly, details regarding surgical judgement including technical details and use of mechanical support could not be captured. Other factors prone to variability such as intensive care unit care and surgeon experience could potentially confound results as well. Finally, the generalizability of these outcomes to other centers is unknown.