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Successful treatment of arrhythmia with β-blocker and Flecainide combination in pregnant patients with Andersen-Tawil syndrome
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  • Pongprueth Rujirachun,
  • Apichaya Junyavoraluk,
  • Manop Pithukpakorn,
  • Bhoom Suktitipat ,
  • Arjbordin Winijkul
Pongprueth Rujirachun
Mahidol University Faculty of Medicine Siriraj Hospital
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Apichaya Junyavoraluk
Mahidol University Faculty of Medicine Siriraj Hospital
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Manop Pithukpakorn
Mahidol University Faculty of Medicine Siriraj Hospital
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Bhoom Suktitipat
Mahidol University Faculty of Medicine Siriraj Hospital
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Arjbordin Winijkul
Mahidol University Faculty of Medicine Siriraj Hospital
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Abstract

Andersen-Tawil syndrome (ATS) is a rare inherited ventricular arrhythmia (VA). Here, we reported two KCNJ2-associated ATS patients who got pregnant and underwent vaginal birth safely. Both individuals had VA, micrognathia without periodic paralysis. β-blocker plus flecainide could be an effective treatment combination when monotherapy failed to control arrhythmia.