Introduction
Andersen-Tawil syndrome (ATS) is a rare autosomal dominant channelopathy characterized by clinical triad of ventricular arrhythmia (VA), periodic paralysis and distinctive dysmorphic features.
Due to the rarity of this condition, less is known about physiologic effect of pregnancy to ATS and arrhythmia. There is no established guideline for prenatal or postpartum treatment and prevention of arrhythmia in ATS, thus the clinical management is challenging1. Here we reported two pregnant ATS patients whose VA could be controlled by antiarrhythmic drug combination.