Discovery Discovery Discovery Discovery Replication-EGEA Replication-EGEA Replication-EGEA Replication-EGEA Meta-analysis Meta-analysis
CpG CHR Great annotation (distance to TSS) Coef SE P N Coef SE P N* P.meta Direction
cg24788483† 10 HABP2 (-401132), TCF7L2 (+201644) -1,31E-02 2,11E-03 4,62E-10 54 -1,348 0,544 0,013 56 (53/3) 8,49E-10
cg15223066 10 ITGB1 (-23896), NRP1 (+354472) -8,56E-03 1,39E-03 6,65E-10 54 -0,658 0,470 0,161 92 (89/3) 1,13E-06
cg26909813 17 RPRML (-605) -2,68E-02 4,15E-03 1,06E-10 54 -0,621 0,539 0,249 95 (92/3) 1,52E-06
cg02341571 15 PATL2 (+150) -1,69E-02 2,71E-03 4,39E-10 54 -0,253 0,388 0,515 64 (62/2) 2,59E-06
cg00269245 16 SLC12A3 (-41116), NUP93 (+93986) 1,13E-02 1,86E-03 1,14E-09 54 0,832 1,109 0,453 70 (68/2) 4,62E-06 ++
cg24833566 4 MTNR1A (-152680), FAT1 (+15608) 1,02E-02 1,71E-03 2,38E-09 54 0,658 0,758 0,386 77 (74/3) 6,87E-06 ++
cg25881850 11 KCNK4 (-1426) -1,23E-02 2,23E-03 3,43E-08 54 -0,838 0,816 0,304 68 (67/1) 9,09E-06
cg24730612 14 FOS (-95503), TMED10 (-6640) -1,47E-02 2,50E-03 4,15E-09 54 -0,260 0,489 0,595 62 (61/1) 1,09E-05
cg23250019 11 SLC29A2 (+818) 2,15E-02 4,00E-03 7,62E-08 54 0,645 0,541 0,234 82 (79/3) 1,61E-05 ++
the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8. the CpG site was replicated with meta P value<1.14×10-7. * N (persA/ComR), N varies from one CpG to another because of the methylC-capture sequencing method used and different QC criteria in EGEA. P.meta: the P value of meta-analysis of results from discovery and EGEA by using weighted Z-scores method. Direction: the direction of regression coefficient in discovery and EGEA. A list of all 129 significant CpG sites identified in discovery cohort and the information of replication in EGEA is shown in Table S8.