11 TREATMENT

To date, there is no well-known, effective & pharmacologically proved treatment of SARS-CoV-2. Different antiviral drugs were administered for 90 % of COVID-19 patients in different reports.17,92,93 Although, major antiviral treatments that were proposed, include lopinavir/ritonavir,17,92-95 oseltamivir, ganciclovir,17,92,93 Arbidol (umifenovir), remdesivir, favipiravir, ribavirin,96chloroquine,96-100hydroxychloroquine,97,100,101 and alpha-interferon.96 Plasma transfusion was also reported for the treatment of corona virus.92 This literature review is subjected to compare the efficacy of major antiviral drugs against the treatment of COVID-19 and choose the most appropriate one to treat SARS-CoV-2.