TABLE 1 Patient Characteristics
Legend:
J = Jacksonville | D = Delaware
M = Male | F = Female
Y = Yes | N = No | NA = Not ApplicableA Values based on vasculopathy scores from the SWiTCH
grading system11EDAS = Encephaloduroarteriosynangiosis
Direct = Direct Surgery (STA-MCA Bypass)B History of medicationC Time from first transfusion on CTT to last follow-up
visitD Time from first transfusion on CTT to stroke event
FIGURE 1 Flow diagram of patient exclusion and treatment group
selection
Legend:
SCD-MMS = Sickle Cell Disease and Moyamoya Syndrome
FIGURE 2 Patient Population Characteristics
Average Age at First Stroke (2a)
Presenting Symptoms (2b)
Medications: Aspirin and Iron Chelation (2c)
Legend:
Abn TCD = Abnormal Transcranial Doppler
TIA = Transient Ischemic Attack
FIGURE 3 Surgical treatment group versus conservative treatment
group Kaplan-Meier stroke-free survival analysis with Logrank test and
follow-up time in years, p=0.146
Legend:
Cum Survival = Cumulative Survival
Cons = Conservative Treatment Group
Surg = Surgical Treatment Group
FIGURE 4 Surgical treatment group versus conservative treatment
group Kaplan-Meier stroke-free survival analysis with Logrank test and
follow-up time in years, pooled with data from Hall et
al8 and Yang et al17 papers, p=0.001
Legend:
Cum Survival = Cumulative Survival
Cons = Conservative Treatment Group
Surg = Surgical Treatment Group