Children
The three months of maximum cases in children were March (10.8%), May (10.8%), and October (10.2%), adding up to 31.8% of childhood diagnoses. The minority of children ALL cases presented in December (5.6%), September (5.9%), and November (6.5%), explaining only 18% of ALL diagnoses (Figure 3A); further analysis of the whole cohort by sex is presented(Figure 3B). In males, three main peaks were found: in July, October (12.1% each) and in March (11%), adding up to 35.2%. (Figure 4A). Females had only one main peak in May, accounting for 14.3%. When classified by risk group, 176 (54.5%) children were high-risk and 147 (45.5%) standard-risk patients. May was the month with the highest peak for high-risk patients (11.8%), while October had the highest peak for the standard-risk group (12.1%). The month with the lowest number of ALL cases for high-risk patients was January (6.25%) and for the standard risk group it was September (4%). (Figure 4B).