FIGURE LEGENDS
FIGURE 1 Children and adolescents with acute lymphoblastic leukemia (ALL) between 2004-2018
FIGURE 2 Diagnoses of ALL with Poisson harmonic regression trend line. Poisson harmonic regression, sinusoidal model post-estimation P-value (Pearson X 2 goodness of-fit)
FIGURE 3A Seasonal variation in month of diagnosis for 394 patients with ALL between 2004 and 2018 stratified by age group (children and adolescents) B Seasonal variation in month of diagnosis for 394 patients with ALL between 2004 and 2018 stratified by sex
FIGURE 4 A Seasonal variation in month of diagnosis for 323 children with ALL between 2004 and 2018 stratified by sex. Three peaks were identified in males, corresponding to March, July, and October. Females exhibited a single peak in MayB. Seasonal variation in month of diagnosis for 323 children with ALL between 2004 and 2018 stratified by risk group; high-risk group had its maximun peak in May, while standard-risk cases prevailed in October. C. Seasonal variation in month of diagnosis for 71 adolescents with ALL between 2004 and 2018 stratified by sex. There was a peak of maximum number of cases in July and a 4.5 to 1 male to female ratio in this month