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Comparison of Echocardiographic parameters with Cardiac Magnetic Resonance Imaging in the Assessment of Right Ventricular Function
  • +12
  • Pradyumna Agasthi,
  • Chieh-Ju Chao, ,
  • Robert J. Siegel,
  • Sai Harika Pujari,
  • Farouk Mookadam,
  • Nithin Venepally ,
  • Panwen Wang,
  • Hasan Ashraf,
  • Francois Marcotte,
  • Lisa Brown,
  • Oksana Semkiv,
  • Ayman Fath,
  • Mohamed Allam,
  • Clinton Jokerst ,
  • Reza Arsanjani
Pradyumna Agasthi
Mayo Clinic Arizona
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Chieh-Ju Chao,
Mayo Clinic Arizona
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Robert J. Siegel
Cedars Sinai Med Ctr
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Sai Harika Pujari
Mayo Clinic Arizona
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Farouk Mookadam
Mayo Clinic
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Nithin Venepally
Mayo Clinic Arizona
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Panwen Wang
Mayo Clinic Arizona
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Hasan Ashraf
Mayo Clinic Arizona
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Francois Marcotte
Mayo Clinic Arizona
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Lisa Brown
Mayo Clinic Arizona
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Oksana Semkiv
Mayo Clinic Arizona
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Ayman Fath
Mayo Clinic Arizona
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Mohamed Allam
Mayo Clinic Arizona
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Clinton Jokerst
Mayo Clinic Arizona
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Reza Arsanjani
Mayo Clinic Arizona
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Peer review status:UNDER REVIEW

09 Jun 2020Submitted to Echocardiography
10 Jun 2020Assigned to Editor
10 Jun 2020Submission Checks Completed
27 Jun 2020Reviewer(s) Assigned

Abstract

Introduction: The right ventricle (RV) strain measured by speckle tracking (RVS) is a novel method of assessing RV function. We compared RVS to RV fractional area change (FAC%), tricuspid annular peak systolic excursion (TAPSE) and Doppler tissue imaging-derived peak systolic velocity (S’) in the assessment of right ventricular (RV) systolic function measured using cardiac magnetic resonance imaging (MRI). Methods: We enrolled consecutive patients who underwent cardiac MRI between Jan 2012- Dec 2017 and a transthoracic echocardiogram (TTE) within 1 month of the MRI with no interval event. Baseline clinical characteristics and MRI parameters were extracted from chart review. Echocardiographic parameters were measured prospectively. TTE parameters including RVS, TAPSE, S’ and FAC% were tested for accuracy to identify impaired RV EF (EF <45% & <30%) using receiver operator curves. Results: The study cohort included 500 patients with mean age 55 yr ± 18 and right ventricular systolic pressure 33.7 ± 13.6 mmHg. The area under ROC for RVS was 0.69 (95% CI 0.63 – 0.75) and 0.78 (95% CI 0.70 – 0.88) to predict RVEF <45% & RVEF <30% respectively. The RV FAC % had second highest accuracy of predicting RVEF among all the TTE parameters tested in study. Conclusion: Right ventricular strain is the most accurate echocardiographic method to detect impaired right ventricular systolic function when using MRI as the gold standard.