CONCLUSION
LAA closure, usually performed for patients with atrial fibrillation significant risk of thrombosis who cannot tolerated warfarin, can be performed safely and simultaneously in selected patients with significant ASD with chronic atrial fibrillation. Performing them together simplifies the procedure and may be performed regardless of the CHADS2, CHA2DS2-VASc and HAS-BLED scores. This study may pave the way for a possible novel indication for left atrial appendage closure. However, larger scale study is indicated before such an indication can be widely recommended.