Acknowledgements
The authors acknowledge the review of the work by Dr Jeremie Guedj of INSERM and Drs Patrick Smith and Kashyap Patel of Certara. The authors are grateful to Jim Gallagher of Certara in the generation of the graphic.
The authors acknowledge review of the work from Drs Dan Hartman and Steve Kern from the Bill and Melinda Gates Foundation and financial support from the Bill and Melinda Gates Foundation.