AUTHOR CONTRIBUTIONS
WZ, H-C H and GL conceived the study and contributed to the design. H-H
Z, T-M M, J-G Z and H-J D contributed to acquisition of samples. H-H Z,
J-G Z, H-J D and T-M M performed experiments. WZ and H-H Z contributed
to data analysis. WZ contributed to writing the manuscript. H-C H and GL
review and editing the manuscript. GL and WZ obtained funding. H-C H
provided technical support and constructive discussion. All authors
approved the final version to be published and agreed to be accountable
for all aspects of the manuscript.