Subjects
We prospectively performed CE-3D-GRE at the onset or at relapse of the
disease, and during remission on four AAV patients who presented with
otologic manifestations as major initial symptoms. Diagnosis for GPA was
made based on the European Medicines Agency (EMEA) vasculitis
classification algorithm of 2007 because it requires characteristic
symptoms of the respiratory tract suggestive of GPA, including otologic
involvement, and positive serology for ANCA, and does not rely on
histological confirmation for diagnosis. Diagnosis of EGPA was made in
accordance with the 1990 American College of Rheumatology (ACR)
criteria.