Scanning protocol of CE-3D-GRE
A dedicated 8-channel head coil was used on a 3.0 Tesla MRI scanner,
with the 3D fast-spoiled gradient-echo sequence (SPGR) (SignaHDxt; GE
Healthcare, Waukesha, WI, USA) or with the 3D fast-field echo sequence
(FFE) (Ingenia CX; Philips Healthcare, Best, the Netherlands). The
parameters for SPGR were as follows: TR/TE = 7.4/2.8 ms; flip angle,
20º; field of view, 20 × 20 cm; matrix size, 288 × 256; section
thickness, 1.5 mm; slice spacing, 1.5 mm; and acquisition time,
110seconds. The parameters for FFE were as follows: TR/TE = 16.0/4.6 ms;
flip angle, 20º; field of view, 22× 22 cm; matrix size, 448× 448;
section thickness, 1.0 mm; slice spacing, 0.5 mm; and acquisition time,
218seconds. Contrast-enhanced images were acquired immediately after an
intravenous bolus injection of 0.1 ml/kg gadobutrol (Gadovist 1.0;
BayerSchering Pharma, Berlin, Germany) or 0.2 ml/kg megluminegadoterate
(Magnescope; Guerbet,Tokyo, Japan).