Subjects
We prospectively performed CE-3D-GRE at the onset or at relapse of the disease, and during remission on four AAV patients who presented with otologic manifestations as major initial symptoms. Diagnosis for GPA was made based on the European Medicines Agency (EMEA) vasculitis classification algorithm of 2007 because it requires characteristic symptoms of the respiratory tract suggestive of GPA, including otologic involvement, and positive serology for ANCA, and does not rely on histological confirmation for diagnosis. Diagnosis of EGPA was made in accordance with the 1990 American College of Rheumatology (ACR) criteria.