Conflicts of interest:
GdT reports grants from National Institute of Allergy and
Infectious Diseases (NIAID, NIH), Food Allergy & Research Education
(FARE), MRC & Asthma UK Centre, UK Dept of Health through NIHR, Action
Medical Research and National Peanut Board. Scientific Advisory Board
member Aimmune. Investigator on pharma-sponsored allergy studies
(Aimmune, and DBV Technologies). Scientific advisor to Aimmune, DBV and
Novartis.
RvR consults for HAL Allergy BV, Citeq BV, Angany Inc, Reacta
Healthcare, Mission MightyMe and has equity in Angany Inc.
SR reports grants from National Institute of Allergy and
Infectious Diseases (NIAID, NIH) to cover parts of a research salary.
HAB reports grants from National Institute of Allergy and
Infectious Diseases (NIAID, NIH), and speaker fees from DBV
Technologies, outside of the submitted work.
CF is Chief Investigator of the UK National Institute for
Health Research-funded TREAT
(ISRCTN15837754)
and SOFTER (Clinicaltrials.gov: NCT03270566) trials as well as the
UK-Irish Atopic eczema Systemic Therapy Register (A-STAR;
ISRCTN11210918) and a Principle Investigator in the European Union (EU)
Horizon 2020-funded BIOMAP Consortium
(http://www.biomap-imi.eu/). He
also leads the EU Trans-Foods consortium and directs the Global Atopic
Dermatitis Atlas (www.atopicdermatitisatlas.org). His department has
received funding from Sanofi-Genzyme and Pfizer for skin microbiome
work. He has also received compensation from the British Journal of
Dermatology (reviewer and Section Editor) and EuroGuiDerm (guidelines
lead).
GL reports grants from National Institute of Allergy and
Infectious Diseases (NIAID, NIH), other from Food Allergy & Research
Education (FARE), other from MRC & Asthma UK Centre, other from UK Dept
of Health through NIHR, other from National Peanut Board (NPB), other
from The Davis Foundation, during the conduct of the study; shareholder
in DBV Technologies, and Mighty Mission Me, personal fees from Novartis,
personal fees from Sanofi-Genyzme, personal fees from Regeneron,
personal fees from ALK-Abello, personal fees from Lurie Children’s
Hospital, outside the submitted work.
AFS reports grants from Medical Research Council (MR/M008517/1;
MC/PC/18052; MR/T032081/1), Food Allergy Research and Education (FARE),
the Immune Tolerance Network/National Institute of Allergy and
Infectious Diseases (NIAID, NIH), Asthma UK (AUK-BC-2015-01), BBSRC,
Rosetrees Trust and the NIHR through the Biomedical Research Centre
(BRC) award to Guy’s and St Thomas’ NHS Foundation Trust, during the
conduct of the study; personal fees from Thermo Scientific, Nutricia,
Infomed, Novartis, Allergy Therapeutics, Buhlmann, as well as research
support from Buhlmann and Thermo Fisher Scientific through a
collaboration agreement with King’s College London.
All the other authors have nothing to disclose .