CONCLUSION
Pregnancy complicated with COVID-19 does not show significant effects on
pregnancy outcomes. No adverse foetal outcomes were observed during the
neonatal follow-up (until 3 months) in the infants born to mothers
infected with COVID-19 during early pregnancy. COVID-19 during pregnancy
may lead to a systemic inflammatory response and hypoxia, resulting in
elevated liver enzymes and placental insufficiency. The placenta has a
potential reserve capacity allowing pregnancy to continue to term.
Although the placenta and decidua express ACE2, the placenta does not
appear be a target organ for SARS-CoV-2. Possibly, the placental barrier
can effectively prevent SARS-CoV-2 from causing intrauterine infection.