1. Introduction
Cystic adenomatoid malformation (CCAM) is a fetal lung malformation. It
has been reported that the incidence of CCAM is between 1:11,000 and
1:35,0001. CCAM is characterized by benign
malignancies or dysplastic lung tumors with excessive growth of terminal
bronchioles and a decrease in the number of alveoli2.
The perinatal mortality rate associated with prenatally diagnosed CCAM
varies widely, ranging from 9% to 49%3. This is
because the clinical characteristics of CCAM vary greatly, from acute
respiratory distress at birth to incidental asymptomatic lesions on a
chest radiograph at any age. Whether asymptomatic CCAM requires surgery
during the neonatal period is still controversial, but it is clear that
surgery is the accepted standard of care for all symptomatic CCAMs, even
in neonates4,5. Infection is the most common
presenting symptom6. We carried out surgical treatment
for symptomatic CCAM patients after the infection had adequately
subsided. CCAM can be treated with open or thoracoscopic resection. To
date, few reports have compared the outcomes of the two surgical methods
for the treatment of CCAM in neonates. Therefore, the purpose of this
study is to compare the preoperative, intraoperative, and postoperative
variables of the two surgical procedures and to determine whether the
two surgical methods have an effect on the outcome of CCAM.