Fig.1. Fig.2 Fig.3 Fig.4 Fig.5
Fig.1 describe, the possible mechanism the formation of virus particles through NA( Nucleic Acid) fragments, Fig.2, and 3, SEM view of Corona, and H1N1 virus , Fig. 4 shows the molecular structure of SARS-COV-2 RNA-virus, Fig.5 shows the SEM view of Wuhan corona clustered .
SEM derived images of Covid-19, SARS-Cov-2, and H1N1 virus shows the similarities of surface antigen, spike protein, where Wuhan corona show no spikes. The spontaneous reaction of viruses, specially corona can be speculated, that due to ss RNA, it will immediately transcribed to form capsid protein and for the multiplications of virus particles in lung cells, using r-RNA of the infected lung cells, after penetration, virus uses 3′ end of ss mRNA and floating r-RNA of the host lung cells to generate envelope. Envelop of Corona is made by glycoprotein as matrix protein. It encapsulates ss RNA of the replicating ssRNA of the virus, after fusions of coat- glycoprotein with lung cell surface membrane attachments OC43 haemagglutinin type virions are released from host cell, as reported, ruptured cell membrane. New virions of corona, transmit the infection via airborne droplets to the healthy recipients. Virus replicates/multiply locally in cells of the ciliated epithelium, causing cell damage and inflammation. The appearance of antibody in serum and nasal secretions follow the infection and increase immunity peaks in the winter as local epidemics and could last for a few weeks or months. The same serotype may return to the same locality after several years. The virus is difficult to isolate. Nucleic acid hybridization tests (including PCR) are now being introduced as control treatment of common colds and within a-symptomatic patients. No vaccines or specific drugs are available till date. Only vaccine with IS element approach could be an alternative solution to face the present crisis, if at all be successful, [7-10]. Coronaviruses are found in avian and mammalian species. They resemble same each other in morphology and in chemical structure. Even coronaviruses of humans and cattle are found same in their antigens, there is no evidence till date that human coronaviruses can be transmitted from cattle and from animals. In animals, coronaviruses invade many different tissues and cause a variety of diseases, as respiratory infections, i.e. common colds. On rare occasions, gastrointestinal coronavirus infection has been recorded among children, but these enteric viruses are not well defined. After an incubation period of about 3 days, corona virus can cause the symptoms of a common cold, including nasal obstruction, sneezing, runny nose, and secretions. Presence of corona in multiple sclerosis are also not well defined including their infections, [11-17]. Wuhan corona SEM picture, Fig.5, represents the similar 026: EPEC bacterial cluster, as they were reproduced by the author during 1983. The curiosity remains, that whether they have the similar adhering and invasive, colonizing nature, as corona on lung epithelial cells, as in 026: EPEC, inspired the author to recapitulate, theoretically the colonial invasive nature of corona as in 026: EPEC. The question is whether, corona has procured similar gene (haemagglutine) of adhering and invasions as in 026: EPEC.