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A Prospective interventional study for the effect of Zinc Sulphate on pain severity and duration in primary dysmenorrhea
  • Ravali Rao ,
  • Jayaraman Nambiar,
  • Murlaidhar Pai
Ravali Rao
Kasturba Medical College Manipal
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Jayaraman Nambiar
Kasturba Medical College Manipal
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Murlaidhar Pai
Kasturba Medical College Manipal
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Abstract

: Objectives: To study for additive effect on decreasing pain severity and duration on supplementation with Zinc Sulphate along with Mefenamic acid in patients with primary dysmenorrhea. Design: Prospective interventional study Setting: The study was conducted at Kasturba Medical College,Manipal Population sample: Young adult women presenting with primary dysmenorrhea Methods: A prospective interventional study was conducted on 102 women presenting to the OBG OPD with complaints of dysmenorrhea. One group of women were given 50mg/day of oral Zinc Sulphate along with Mefenamic acid on the first three days of menstrual cycle and the other group received Mefenamic acid alone. Main outcomes:Their pain severity as per visual analogue scale and duration were compared over three menstrual cycles. The quality of life of these participants was monitored and compared post treatment. Results: This study has shown a significant improvement in pain severity and duration over three menstrual cycles in patients on Zinc Sulphate and Mefenamic acid when compared to Mefenamic acid alone with p<0.001. There was a significant improvement in the quality of life in performing usual activities, discomfort and anxiety. Conclusion: Addition of zinc sulphate to mefenamic acid in patients with primary dysmenorrhea significantly reduces the pain severity and duration and also improves the quality of life. Thus, can be used as an additional method for treating dysmenorrhea. Key words: Primary dysmenorrhea, Zinc sulphate, Quality of life