Figure legend
Figure 1 . A. Targetoid eruption suggestive of erythema
multiforme (day 1). B. Toxic desquamation (day 6). C.SPT-delayed reaction to ivacaftor/lumacaftor (72 hours). D.IDT-delayed reaction to piperacillin/tazobactam (Tazocin) after 24
hours. E. Positive patch test at 48 hours to
tezacaftor/ivacaftor (top) and ivacaftor (bottom) F &G. LTT.
PBMC were cultured with drugs for 7 days. T-cell proliferation assessed
using thymidine incorporation and beta-counter. H&I.Interferon-γ secretion assessed by ELISpot. J-M. Chemical
structures of drugs.