Although hepatoblastoma constitutes most of hapetic tumours in chidren,
other types of tumors are often observed in older patients. We report a
case of a 10-year-old Japanese boy with a transitional hepatic tumour
consisting of both hepatoblastoma and hepatocellular carcinoma. After
surgery and chemotherapy with cisplatin and pirarubicin, the tumour
regressed, however, new tumours in the liver evolved with element of
hepatocellular carcinoma. He died as a result of hepatic failure afte
lenvatinib and drug-eluting transcatheter arterial chemoembolisation 18
months after diagnosis. Examinations of a panel of genomic alterations
did not identify any therapeutic targets.