NP: nasopharyngeal; OP: oropharyngeal.
Figure legend: The number of samples with and without detectable SARS-CoV-2 RNA are aggregated by sample type, collection day post symptoms onset (dps) and disease severity. Sampling for patients with symptoms or clinical course described in the original publications as mild, moderate, common, or typical are shown in circles: a total of 1627 samples from 173 adults. Sampling for severe or critically ill and/or admitted to the ICU are shown in squares: a total of 1150 samples from 44 adults. Asymptomatic patients were excluded. Sample types are as follows: NP swab (nasopharyngeal/midturbinate/nasal swab), OP swab (oropharyngeal/throat swab), NP+OP swab (both swabs collected in one tube or results published aggregated), sputum (induced/spontaneous sputum), stool, anal swab (anal/rectal swab), blood (serum, plasma, whole blood or not specified), urine. Sample collection dps are shown as stated by the authors, and if unavailable extracted from timeline descriptions.
Figure 2. Heatmaps of mild and severe laboratory confirmed COVID-19 cases (n=217) with positive and negative RT-PCR results in different sample types (n=2777) by days post symptoms onset.