Conclusion:
Cardiac tamponade is a rare complication of COVID-19 infection. Physicians must be cognizant of this possibility in patients with cardiovascular decompensation. Ultrasonography can aid in rapid diagnosis, and drainage of pericardial fluid and can result in clinical improvement. Short-term prognosis appears to depend upon ventricular function. Role of corticosteroids, NSAIDs, and immune modulators remains unclear in this subgroup of COVID-19 patients, but may have a role in preventing the development of ventricular failure caused by the marked inflammatory response and stress cardiomyopathy.